Lupus is a chronic and systemic inflammatory disease. It is an immune pathology of unknown origin that affects the joints and muscles and can damage the skin and almost all organs ( heart, lung, kidney and brain). Specifically, lupus disease causes pain and swelling in the hands, wrists, elbows, knees and feet. The patient also suffers from fatigue, fever, weight loss and skin conditions. Also, depending on the affected organ, manifest different symptoms. There are two types of lupus: systemic lupus erythematosus, with episodes of inflammation in the joints, tendons and other connective tissues and organs;and cutaneous lupus erythematosus, characterized by well-defined on the skin red spots round edges. Corticosteroids are considered the basic treatment for lupus.